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Your doctor may decide not to use IV metronidazole if you have uncontrollable high blood pressure (resistant hypertension), congestive heart failure, or significant fluid retention
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Although the presence of MNNG can markedly increase the rate of mutation, it appears that the efficiency of ALE was not associated with the genetic diversity of the parental strain and that neither the MNNG treatment in a single high dosage nor a continuous addition of the mutagen contributed to GSH accumulation
