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Because DSIP has not been thoroughly studied in humans, people who are pregnant or breastfeeding, have significant medical conditions, or take multiple medications should avoid using it unless advised by a qualified healthcare professional
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In animal brain cell cultures treated with corticosterone (the animal equivalent of cortisol), a GR/Bcl-2 complex is formed

Short-chain fatty acids protect against high-fat diet-induced obesity via a PPAR-dependent switch from lipogenesis to fat oxidation
