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Description
N.FalckJ

Nitrotyrosine within the infected, nitric oxide-generating macrophages, may be enhanced by GSH actions: (a) reducing the protein disulfides, and/or glutathionylating the free protein thiols allows for some unfolding, as intramolecular and interchain disulfides are reduced and/or glutathionylated

Palamara et al., 1995, 1996

In a systematic review with meta-analysis that aimed to synthesize the existing knowledge between antioxidants and the pulmonary function of individuals with CF, the authors recommended the administration of NAC (primarily by inhalation) as an adjunct to treatment, as it became evident that oral supplementation of NAC exhibited beneficial effects in preventing deterioration of lung function, but not significantly
