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5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT) developed at the University of Texas Medical Branch by Neelakantan and colleagues as part of a medicinal-chemistry program targeting NNMT for metabolic-disease research

Gastric acid releases vitamin B12 from the food that you consume, which becomes a problem for some older adults because they produce less stomach acid as they age, thereby increasing their risk for B12 deficiencies

5-Amino-1MQ allows researchers to study these effects at the enzyme and cellular levels under laboratory conditions

Well also talk about how to dose it correctly