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Description
TCTP-PTD also has ability to transport various types of cargo molecules, including peptide, protein, and siRNA, both linked covalently and non-covalently (
Second: the short plasma half-life (~30 min) was insufficient, by the time the fragment circulating in the blood was supposed to act, it had already been metabolized
Many clinical useful drugs are also potential substrates for GST and development of drug resistance can frequently be a key element in treatment failure
JCI Insight 8 , e167274 (2023)
