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In December 2025, Nektar Therapeutics reported topline data from its Phase 2b REZOLVE-AA trial evaluating rezpegaldesleukin in patients with severe-to-very-severe AA

S2CID 52977621

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In the setting of isolated methylene blue administration purple urine raises the concern for acute hemolytic anemia secondary to glucose-6-phosphate dehydrogenase deficiency [1]
