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Similar findings were observed in a further prospective, dual-centre study by Penicka and colleagues in which 258 asymptomatic patients with moderate or severe primary MR defined by echocardiography underwent CMR and were followed up for a median of 5 years 13
This is a benign cosmetic effect, not a sign of toxicity or organ injury
Evidence suggests that these metabolic deficits can occur before AD pathology becomes evident [167]
The body makes ALC in small amounts, but as we age, levels decline
