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doi: 10.3389/fimmu.2024.1338922 Received 16 November 2023 Accepted 02 February 2024 Published 15 February 2024 Volume 15 - 2024 Edited by Fuminori Tokunaga, Osaka Metropolitan University, Japan Reviewed by Daisuke Oikawa, Osaka Metropolitan University, Japan Shivalee Duduskar, National Institutes of Health (NIH), United States Updates Copyright 2024 Wang, Chen, Bao, Yao, Wen, Xu, Chen, Guo, Pang, Zhou and Zhou

Results depend on lifestyle factors such as sun exposure, diet, stress, and skincare habits

PHARMACOKINETICS The standard dose of a drug is based on trials in healthy volunteers and patients with average ability to absorb, distribute, and eliminate the drug (see Clinical Trials: The IND and NDA in Chapter 1 )

Splitface studies involving subcision and other modalities of scar revision on the contralateral side of facial skin were included provided only one treatment modality is used on each side of the skin