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DR results from high levels of glucose, and an increase flux through the HBP, leading to higher levels of UDP-GlcNAc, which in turn increase O -GlcNAc modification resulting in altered cellular functions, especially in pericytes (63)

Therefore, leptin, which has been until now barely investigated in hemorheological research, may be one of the important physiological regulators of red cell rheology, involving it in regulatory loops that link energy stores and circulation

cerevisiae can live in environments with varied levels of oxygen (from the complete absence of oxygen (anoxia) to the typical concentration for atmospheric air, i.e