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The copper component contributes essential cofactor activity for enzymes involved in melanin synthesis and structural protein cross-linking, supporting both pigmentation and mechanical properties of hair fibers

Hyperthyroidism is also common, but has the opposite effect, making more than enough thyroid hormone and disrupting thyroid function

For example, there are nuclear import signals for proteins to be sent to the nucleus, and nuclear export tags for proteins that need to go to the cytoplasm
