l-carnitine cancer risk Clinical Significance of Carnitine in the Treatment of Cancer: From Traffic to the Regulation - Farahzadi - 2023 - Oxidative Medicine and Cellular Longevity Serum carnitine and cancer risk:

60, 61 CTP1C expression displays an inverse correlation with the activation of mTOR pathway and attenuates tumor sensitivity to rapamycin (a mTOR inhibitor), 18 which suggests that the CPTIC-involved pathway parallels to mTOR-enhanced glycolysis

doi: 10.1172/JCI117488 16 CarracedoACantleyLCPandolfiPP

The randomized and placebo-controlled design of all included trials and the double-blind design of most of them can also be other strengths and due to the RCT nature of the studies, the drugs used by the patients (especially in diabetic patients), the diet and the level of physical activity of the participants were controlled and in fact their effects were considered and it can be said that the pure effects of L-carnitine was evaluated

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