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In vitro assays of purified PDHC Purified porcine PDHC (Sigma) was used for in vitro assays of RNS-mediated inhibition of PDHC
Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and b-arrestin1
The first is catalyzed by glutamate cysteine ligase (GCL), which ligates cysteine to glutamate to produce -glutamylcysteine
However, in contrast to our results, such cellular mechanisms have been addressed in response to acute NAC administration and do not exhibit cell-type specificity
