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By changing the structure of the binding site, receptors may conform to a structure that CBD is capable of interacting with, only after binding of another ligand (Kondra et al

The mechanism by which sulfation stimulates especially the IRD of different substrates remains unclear

doi: 10.3389/fphar.2020.602364 Received 03 September 2020 Accepted 02 December 2020 Published 08 February 2021 Volume 11 - 2020 Edited by Cheorl-Ho Kim, Sungkyunkwan University, South Korea Reviewed by Young-Ji Shiao, National Research Institute of Chinese Medicine, Taiwan Ulrike Lindequist, University of Greifswald, Germany Updates Copyright 2021 Das, Shin, Leyva-Gmez, Prado-Audelo, Cortes, Singh, Panda, Mishra, Nigam, Saklani, Chaturi, Martorell, Cruz-Martins, Sharma, Garg, Sharma and Patra

Glucosamine or chondroitin taken as additives to drinks were not included