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Ectopic cysts show significant volumetric reduction, the endometrial epithelium exhibits clear atrophy and glandular simplification, and the expression of heat shock protein 70 (HSP70), a chaperone that stabilizes misfolded proteins and promotes lesion survival under stress, as well as vascular endothelial growth factor (VEGF), a key driver of pathological neovascularization, is significantly reduced in ectopic tissues (Yadav et al., 2022)

In contrast, at high concentrations (600 M in vitro ), CGA induces a state of functional iron deficiency by depleting the labile Fe 2+ pool

Screening procedures help researchers maintain controlled conditions and improve consistency across studies

Another relevant lab test is the MMA test, which stands for methylmalonic acid test