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In this context, GDAP1 has been linked to mitochondrial fission and axonal transport, bioenergetics, redox sensing, calcium signaling, neuroinflammation, and the regulation of MCSs [12,13,14,15] (Figure 1), positioning it as a multifunctional regulator at the crossroads of mitochondrial dynamics and inter-organelle communication

The pharmacological availability of the pHPMA nanoparticles was 6.61%, more than 2 times that of the uncoated NCs (2.60%), validating the function of the pHPMA coating

Since inflammation is associated with poor cancer prognosis, this was an important finding

Importantly, this pediatric-focused study showed that miRNA alterations start early and are not restricted to adult populations, suggesting that miRNA panels could help with early detection and prevention strategies in adolescents
