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Any skin that is bruised, red, hard, lumpy, scarred, heavily tattooed, or broken

Prolonged mitochondrial Ca overload triggers opening of the mitochondrial permeability transition pore (mPTP), causing increased membrane permeability, loss of membrane potential, mitochondrial swelling, membrane rupture, and further ATP depletion

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Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID
