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Intracoronary infusion of nor-NOHA (0.1 mg/min) also enhances endothelium-dependent vasorelaxation in coronary arteries in patients (age 69 3) with CAD (n = 16), or CAD and T2D (n = 16), but not in healthy subjects (n = 16) (Shemyakin et al., 2012)

20, 745754 10.1038/s41556-018-0124-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 105.Shadel G.S

Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways

Conversely, when the Merlin/NF2 gene is deleted, SLC7A11 protein levels and cystine uptake significantly increase, leading to increased cell death under glucose-deficient conditions and revealing the dynamic interplay between metabolic stress and antioxidant defense
