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Sun L, Yau H-Y, Wong W-Y, Li RA, Huang Y, Yao X (2012) Role of TRPM2 in H(2)O(2)-induced cell apoptosis in endothelial cells

doi: 10.1186/s12943-024-02198-2
doi: 10.1001/jama.2010.1706

UA inhibits papillary thyroid carcinoma (IHH-4 and TPC-1) cells by classical mechanisms, which inhibits EMT by down-regulating fibronectin-1 (FN1), blocks invasive behaviors of cancer cells, reduces the protein expression of Bcl-2, and activates Caspase-3, which further promotes apoptosis [1065]
