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To prove the importance of these biochemical pathways, a recent research enrolling 1,602 patients with SUD compared with 2,858 non-SUD patients showed that there is an acceleration of age-related and degenerative pathologies in many tissues, evaluated by the higher levels of serum glucose, HbA1c elevation, fructosamine, concentrations, and microalbumin levels, all of them being biomarkers of age (Reece, 2013)

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The incorporation of CeO 2 nanoparticles enhanced its activity
