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The co-crystallized fragments found in sub-pockets A-C and the protein were used as input for the SZMAP, Gameplan, and vBrood applications and visualization in MOE

Additionally, CoQ10 supplements showed promising results in a small group of de novo PD patients during phase II clinical trials although no follow up study has been published (Shults et al., 2002)

doi: 10.2147/IJN.S50683

APAP and erastin also induced significant cytotoxicity in Hepa RG, with IC 50 of 9.8 mM and 39 M, respectively (Fig