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It creates new blood vessels (VEGF) to deliver nutrients, accelerates collagen synthesis for stronger cartilage, and stabilizes cellular membranes to stop joint deterioration

With needleless systems, the stress and anxiety often associated with injections can be significantly reduced, potentially improving treatment adherence and health outcomes

For comparisons between three or more groups, one-way analysis of variance (ANOVA) or Kruskall-Wallis tests were used, followed by the multiple comparison tests of Tukey or Dunn, for parametric or non-parametric data, respectively

Drug interactions: No known significant interactions