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For detailed reviews of this topic, the reader is referred to recent reviews focused on this topic (103, 176, 220, 238, 243, 278)
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Mice deficient in -glutamyl transpeptidase have been generated, and these animals exhibit glutathionuria, glutathionemia, growth failure, cataracts, lethargy, shortened life span, and infertility (Lieberman et al., 1996
Int J Mol Sci 2013;14(10):21021-21044
