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Description
Cellular senescence is widely recognized as a key factor in the aging process, and it can be activated by factors such as oxidative stress, telomere shortening, and oncogene expression [198]
Our empirical approach in SSc with application of RTX 2 weeks after the last teclistamab dose resulted in effective depletion of peripheral B cells throughout the observation period, and none of the patients with SSc demonstrated evidence of disease activity during follow-up
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Am J Kidney Dis 79:717727
