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Description
While these observations provide insight into potential mechanisms, their translation to human cardiovascular outcomes has not been fully established

Nature Medicine, 14 (5), 504506

Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy

doi: 10.1016/j.est.2023.108597 284 ChakrabortyS
