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Ablation of hepatocyte Smad1, Smad5 , and Smad8 causes severe tissue iron loading and liver fibrosis in mice

Modified from Jonas et al, 2017 (13)

If you receive a stem cell transplant, your provider may use your own healthy stem cells or donated stem cells

These systems may represent new horizons for compounds that have not been clinically tested thus far or that have previously failed in clinical settings as potential ATs
