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USA 116 , 2424224251 (2019)
Aktivitas ini nonstop yang menyebabkan stress yang berkelanjutan pada tubuh dan setiap sel harus berespon atau menderita kerusakan
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
Additionally, metformin modulates immune function and inhibits excessive inflammation, such as by reducing levels of pro-inflammatory cytokines like IL-6 and TNF-, thereby alleviating cytokine storm-induced insulin resistance (141, 142)
