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Although many of the genes up- and downregulated by GSTP1 deletion are associated with the RAS/MAPK pathway (Supplementary Table 1), we did not detect a significant difference in RAS/MAPK pathway activation, using a quantitative RAF-1- binding/Ras GTPase ELISA to assess pathway activation in GSTP1 knockdown cells (data not shown)
They observed that the selected LNPs could deliver mRNAs and induced significant expression of the target protein in the liver

Overnight transdermal scopolamine patch administration has no clear effect on cognition and emotional processing in healthy volunteers

And because NACA can be administered at a lower dose, the drug has a greater therapeutic index and lowers the risk of side effects traditionally associated with NAC
