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We hope that our work will bring more attention to how organelles and their metabolites are relevant to cancer biology, says Kivan Birsoy, head of the Laboratory of Metabolic Regulation and Genetics at Rockefeller
Published 2018 Apr 1
However, its reactivity has a cost: O 2 strips electrons from biological macromolecules causing the formation of reactive oxygen species (ROS), which induce intracellular damage [24]
Hydrogen sulfide protects cardiomyocytes from doxorubicin-induced ferroptosis through the slc7a11/gsh/gpx4 pathway by keap1 S-sulfhydration and nrf2 activation
