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[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Wu Y, Yi M, Niu M, Mei Q, Wu K
GHK-PEG treatment, on the other hand, stimulated apoptosis by 3.2 0.80 and 4.9 0.9 fold at 1 and 10 nM, respectively
It also promotes growth hormone release and prevents the breakdown of protein
The association of Fe 2+ with lipoxygenases (LOX, a dioxygenase containing non-heme iron) can lead to oxygenation of polyunsaturated-fatty-acids (PUFA), such as arachidonic acid present in phospholipids, and trigger lipid peroxidation-induced ferroptosis (Kagan et al., 2017)
