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(2021) employed tandem mass tag proteomics (TMT) and mass spectrometry (MS) to analyze PBMC, identifying differential expression of proteins regulated by the liver X receptor-retinoid X receptor (LXR/RXR) pathway, which modulates lipid metabolism and inflammation, potentially influencing the expression of pro-inflammatory cytokine genes (Schulman, 2017)

Epigenetic Therapy: Azacytidine and Decitabine in Acute Myeloid Leukemia

Following harvest, washing, and resuspension in PBS with 1% BSA, lipid peroxidation levels were evaluated and quantified through flow cytometry (FACSCanto TM II, BD Biosciences)
Cumulative concentrationresponse curves were generated for ACh (endothelium-dependent relaxation) and sodium nitroprusside (SNP