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Description
In this therapeutic ADC, the thioether linker contains cyclohexane and a maleimidomethyl group (maleimidomethyl cyclohexane-1-carboxylate, MCC linker) complexed with a thiol-containing maytansinoid payload (DM1)
Paraffin sections (4 m thick) were used to detect cytokine levels by H&E stain and immunohistochemical (IHC) analysis
PMID 33669824

714 min 7090 % B
