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The systematic review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42024554513 (Available from) ( 2.2 PICOs question The primary research question addressed in this review was: What is the effectiveness of sublingual/oral administration of Vitamin B12 alone or compared to other forms of administration (e.g., intramuscular injection)?

[7] Intramuscular injections , prescribed for severe deficiency or malabsorption conditions, are administered by healthcare professionals according to specific treatment schedules outlined in the BNF
[DOI] [PubMed] [Google Scholar] 142.Matzinger P, Tolerance, danger, and the extended family

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