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It is so effective that best to do in the morning
This is the classic look of tirzepatide/B12 formulations and is entirely normal

Specific clinical scenarios where injections are the standard of care include pernicious anemia, severe malabsorption syndromes, post-bariatric surgery when oral supplementation has failed, and critically low serum B12 levels accompanied by neurological deterioration

In about a month, she sent him a note on the patient portal saying that the initial dose, while tolerated, was not very helpful
