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The effects of co-administration of probiotics and prebiotics on chronic inflammation, and depression symptoms in patients with coronary artery diseases: a randomized clinical trial

[55], showed that rats, orally receiving radiolabeled LC, metabolized it to -butyrobetaine (up to 31% of the administered dose, present primary in feces) and TMAO (up to 23% of the administered dose, present primary in urine)

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[PMC free article: PMC3443707] [PubMed: 22993667] (26 year old man with HIV infection developed jaundice shortly after increasing his intake of herbal pills from 24 to 48 per day [bilirubin 10.4 mg/dL), ALT 1648 U/L, Alk P 154 U/L, INR normal], resolving within 3 weeks of stopping herbals)