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Description
There are some exceptions: ruminants can produce it in their second stomach through the microbiota present there (requiring a micronutritional dietary precursor, cobalt), or fish from their producing microbiota, through the intake of phytoplankton, or by eating other fish

E., Backus, E

Not ideal for larger or oily solutions that require deeper muscle penetration

SAM and methyl-donor pools laboratory work has tracked changes in cellular SAM, SAH and 1-methylnicotinamide levels following NNMT inhibition
