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Description
Theoretical concerns about chronic NNMT inhibition include effects on the metabolism of other quinolinium and methylpyridinium endogenous metabolites and on the broader cellular methylation landscape

Skin type isnt a factor because injections, not the skin surface, go into the muscle
Risk increases with poor injection hygiene, reuse of needles, or injection into non-sterile sites

There isnt any information about how often lipohypertrophy may happen in people using biologics for eczema