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Receptor-mediated uptake : In the distal ileum, IF-B12 complexes bind to cubam receptors on enterocytes, allowing active transport into circulation

doi:10.1186/gb-2002-3-5-research0025

With a 10mg/mL concentration (1mL of water added), that 4mg dose requires drawing 0.4mL, which equals 40 units on a standard U-100 insulin syringe