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The pathophysiology associated with this increased sensitivity to pain has been extensively studied and is thought to be related to CNS dysregulation manifesting at both the cerebral cortex and spinal cord levels [126]

Misdiagnosis of PKD as epilepsy occurs often because the paroxysmal movements are thought to be an epileptic presentation

MIP-1 was selected for the initial screening test to diagnose diseased patients and controls with diagnostic rates of 81.6% and 68.4%, respectively