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First, because 4MP causes considerable phospho-JNK inhibition which negatively impacts p53 activation and necrosis 92 , we considered that 4MP causes a conservative 80% decrease of p53 activation and simulated this by multiplying the phosphorylation rate of p53 with parameter k 4MP JNK = 0.2 (i.e., decreasing the phosphorylation rate)

Some people need weekly injections for 4 weeks, followed by maintenance doses

Review A review is always booked around two weeks later to assess your result and make any small adjustments if needed

Chemical priming by isothiocyanates protects against intoxication by products of the mustard oil bomb