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In 2000, the prevalence of high myopia was 2.7%, and it is projected to 9.8% by the year 2050 (Rudnicka et al., 2016)
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A recent bibliometric review indicates that sulforaphane is the most cited natural product activator of Nrf2 signaling [42]
Under pathological conditions, such as in PD, the level of ROS outpaces the compensatory mechanisms
This multi-target or new-mechanism mode of action increases the difficulty of drug resistance and is expected to delay or overcome the problem of drug resistance to a certain extent
