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Description
Clinical data from the SURMOUNT trials confirms that tirzepatide dual mechanism produces greater weight loss than semaglutide GLP-1-only approach

Statistics and software Non-omics statistics were run in GraphPad Prism (v9, www.graphpad.com) and explored main effects of exercise, NNMTi treatment, and an interaction

Sources Weight loss surgery (2025) NHS [accessed 27 October 2025] Tirzepatide for managing overweight and obesity (2024) NICE [accessed 27 October 2025] Bariatric Surgery Frequently Asked Questions (2025) NHS North Bristol [accessed 27 October 2025] Weight Loss Surgery Prices (2025) Ramsay Health [accessed 27 October 2025] Having an operation (surgery) (2024) NHS [accessed 27 October 2025] Dumping syndrome (2025) Mayo Clinic [accessed 27 October 2025]

doi:10.35541/cjd.20201078 19
