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doi: 10.1016/j.mib.2013.06.003, PMID: [DOI] [PubMed] [Google Scholar] Nanda N., Bobby Z., Hamide A

To maintain their thiol redox homeostasis, they contain millimolar concentrations of the dithiolic polyamine-conjugate N 1 , N 8 -bis(glutathionyl)spermidine, known as trypanothione [T(SH) 2 ] (Fig

On the other hand, overexpression of Nrf2 (transcriptional regulator of seleno-GPxs) contributed to the increase in the radioresistance and stemness in glioma stem cells (GSCs) by upregulating GPx1 and decreasing the cellular ROS level

Zu viel des Guten knnte ins Gegenteil umschlagen, da Antioxidantien in zu hoher Dosis oxidativ wirken knnen