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Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
Additionally, Etidronate, Melatonin, and Albendazole were excluded due to poor bioavailability 82,83,84 , and Eplerenone was excluded due to solubility concerns 85
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