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The results of this study suggest the existence of epistatic actions between folate metabolism enzymes within two key metabolic pathways: those associated with DNA synthesis and repair, as well as remethylation processes

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update. Clinical Pharmacology and Therapeutics , vol

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