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nadph increase and glutathione levels u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Blocking glutathione regeneration: Inorganic NADPH

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nadph increase and glutathione levels u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Blocking glutathione regeneration: Inorganic NADPH

GSTs are also involved in the phase I detoxification process such as dehydrochlorination of 1,1,1-Trichloro-2,2-bis( p -chlorophenyl) ethane (DDT) to less toxic 1,l-Dichloro-2,2-bis( p -chlorophenyl) ethylene (DDE) [22, 43, 44]

nadph increase and glutathione levels u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Blocking glutathione regeneration: Inorganic NADPH

We found a positive effect of AOX treatment on spontaneous pregnancy rate (OR 1.97 [95% CI: 1.28, 3.04]

nadph increase and glutathione levels u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Blocking glutathione regeneration: Inorganic NADPH

The enzyme GR then reduces the oxidized form of glutathione, glutathione disulfide (GSSG), to GSH with NADPH as the reductant (Foyer and Halliwell, 1976)

nadph increase and glutathione levels u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Blocking glutathione regeneration: Inorganic NADPH

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