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nadph increase and glutathione levels u87 cells Disruption of homeostasis by total flavonoids from Adinandra nitida Merr. ex Li leaves triggers ROS-dependent p53 activation leading to apoptosis in non-small cell lung cancer Blocking glutathione regeneration: Inorganic NADPH
Description
R.TimermanA

GSTs are also involved in the phase I detoxification process such as dehydrochlorination of 1,1,1-Trichloro-2,2-bis( p -chlorophenyl) ethane (DDT) to less toxic 1,l-Dichloro-2,2-bis( p -chlorophenyl) ethylene (DDE) [22, 43, 44]

We found a positive effect of AOX treatment on spontaneous pregnancy rate (OR 1.97 [95% CI: 1.28, 3.04]

The enzyme GR then reduces the oxidized form of glutathione, glutathione disulfide (GSSG), to GSH with NADPH as the reductant (Foyer and Halliwell, 1976)
