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Description
Research demonstrates that NNMT expression increases significantly with advancing age, particularly in metabolic tissues, contributing to the progressive decline in NAD+ levels observed during aging

Put plainly, the off period is not there because the compound stops working it is there because no one can point to human data showing that running it indefinitely is safe, and a scheduled break is the honest way to respect that gap

By targeting NNMT and supporting NAD+ levels, it addresses cellular energy metabolism rather than manipulating appetite or stimulating the nervous system

M., Gonzlez M