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CD4+ and CD8+ T cells from THO mice homed more efficiently to lymph nodes than their control counterparts, and induced strong and potent detrimental immune responses that caused DED-related clinical symptoms in the recipient animals
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Blood, liver, heart, and skeletal muscle were taken at sacrifice for analysis of carnitine, electron microscopy, and oxidation studies

Genetic CPT1A deficiency is a very rare occurrence, but patients generally present with hypoketotic hypoglycemia and hepatic encephalopathy due to defects in long-chain FAO (27)
