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While animal studies show a good safety profile, a theoretical risk involving its pro-angiogenic effects and potential cancer promotion is a point of consideration, though no evidence has supported this risk in practice

in Current Pharmaceutical Design documented BPC-157s multi-organ protective effects across more than two decades of preclinical research, with particular focus on its remarkable stability in gastric acid a property that distinguishes it from most biologically active peptides and enables oral delivery studies in animal models [1]

10.3390/brainsci12101287 23 MorganH

Mechanisms of age-related decline in insulin-like growth factor-I dependent proteoglycan synthesis in rat intervertebral disc cells