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People with certain health conditions should avoid these injections or consult their healthcare provider before use

- People with significant liver disease (the 9-month monkey toxicology study showed dose-dependent periportal vacuolation in hepatocytes that the FDA flagged as a possible safety signal)

MOTS-c is studied as a mitochondrial-derived peptide involved in metabolic signaling, glucose-related pathway research, exercise adaptation models, and mitochondrial stress response

These vectors provided reasonable levels of -globin transgene expression in vitro , but the transduction of mouse hematopoietic stem cells (HSCs) was suboptimal, resulting in limited and variable expression of the -globin gene in vivo [133], [134]