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Description
Because healthy proliferating cells do not rely on sustained FOXO4p53 sequestration for survival, they are less affected in experimental models

After treatment, cells were washed twice with PBS, detached using 0.25% trypsin-EDTA, and transferred into polystyrene tubes

Subcellular fractionation of membrane-enriched fractions Membrane-enriched fractions were fractionated using an iodixanol gradient

In summary, administration of live helminths or helminthic products in EAE animal models appears to reduce the incidence and progression of EAE if administered before the active phase of the disease (61, 107, 115, 116)